Functionalization of graphene: does the organic chemistry matter?

• Artur Kasprzak,
• Agnieszka Zuchowska and
• Magdalena Poplawska

Beilstein J. Org. Chem. 2018, 14, 2018–2026, doi:10.3762/bjoc.14.177

• misunderstandings from the reported covalent functionalization methods are discussed, and a direct link between the reaction mechanisms and the basic principles of organic chemistry is taken into special consideration. Keywords: characterization; functionalization; graphene; modification; synthesis design

A new paradigm for designing ring construction strategies for green organic synthesis: implications for the discovery of multicomponent reactions to build molecules containing a single ring

• John Andraos

Beilstein J. Org. Chem. 2016, 12, 2420–2442, doi:10.3762/bjoc.12.236

• each partition type. Hence, the construction of hydrocarbon skeletons, containing no pivoting nucleophilic or electrophilic atoms, yields the highest range of possible assemblies and hence the greatest opportunities for creativity and novelty in synthesis design. This explains why such target compounds

Properties of PTFE tape as a semipermeable membrane in fluorous reactions

• Brendon A. Parsons,
• Olivia Lin Smith,
• Myeong Chae and
• Veljko Dragojlovic

Beilstein J. Org. Chem. 2015, 11, 980–993, doi:10.3762/bjoc.11.110

• : perfluorinated solvents; phase screen; PTFE; semipermeable membrane; synthesis design; Introduction Fluorous reactions are a relatively new addition to the portfolio of synthetic methods [1][2][3][4][5]. In a fluorous triphasic reaction, introduced by Curran in 2001, a fluorous phase screen was used to

Glycosylation efficiencies on different solid supports using a hydrogenolysis-labile linker

• Mayeul Collot,
• Steffen Eller,
• Markus Weishaupt and
• Peter H. Seeberger

Beilstein J. Org. Chem. 2013, 9, 97–105, doi:10.3762/bjoc.9.13

• 30 min, eluents: H2O and MeCN, detection at 254 nm; the double peak for 39 is caused by an anomeric mixture). Solid-phase synthesis of biopolymers. X represents a reactive site such as an amino group for peptide synthesis or a hydroxy group for oligonucleotide and oligosaccharide synthesis. Design of